Dr. Jorge Luna-Guerra, M.D.

Cardiology

EDUCATION:

Medical Doctor: School of Medicine [Facultad de Medicina],

Universidad Autónoma de Baja California.

Mexicali, Baja California. MEXICO.

August 1985 to June 1992.

Degree conferred: Physician and Surgeon [Medico Cirujano]

POSTGRADUATE TRAINING:

Residency: Internal Medicine

Instituto Nacional de la Nutrición.

Mexico City. MEXICO.

Duration: March 1993 to February 1996.

Degree conferred: Specialist in Internal Medicine

Universidad Nacional Autónoma de México.

Mexico City. MEXICO.

Fellowship: Cardiovascular Medicine.

Instituto Nacional de Cardiología.

Mexico City. MEXICO.

Degree conferred: Sub-specialist in Cardiology

Universidad Nacional Autónoma de México.

Mexico City. MEXICO.

Duration: March 1996 to February 1999.

Fellowship: Cardiac Catheterization (Hemodynamics).

Instituto Nacional de Cardiología.

Mexico City. MEXICO.

Degree conferred: Sub-specialist in Invasive Cardiology

Instituto Nacional de Cardiología.

Mexico City. MEXICO.

Duration: March 1999 to August 1999.

Post Doctoral Fellowship: Cardiovascular Medicine (Research)

Stanford University School of Medicine

Supervisors: Peter J. Fitzgerald, MD, PhD; Paul G. Yock, MD

Degree conferred: Specialist in Cardiovascular Medicine

Stanford University School of Medicine.

Stanford, CA, U.S.A.

Duration: October 1999 to April 2001.

Post Doctoral Fellowship: Interventional Cardiology (Clinical Training)

Stanford University School of Medicine

Supervisor: Alan C. Yeung, MD

Degree conferred: Sub-specialist in Interventional Cardiology

Stanford University School of Medicine.

Stanford, CA, U.S.A.

Duration: May 2001 to April 2003.

RESEARCH EXPERIENCE

Research Assistant: Liver Unit, Department of Gastroenterology.

Instituto Nacional de la Nutricion.

Mexico City. MEXICO.

Supervisor: Misael Uribe, M. D.

Activities: Clinical Research:

- Liver Cirrhosis and Chronic Hepatitis

- Portal Hypertension, Liver Hemodynamics

- Transjugular liver biopsy

Experimental Research:

- Liver cirrhosis and portal hypertension induced by

bile-duct ligation

- Portal hemodynamics

Duration: August 1991 to February 1993.

Research Fellow: Division of Cardiovascular Medicine.

Stanford University School of Medicine.

Stanford, CA.

Supervisors: Peter J. Fitzgerald, MD, PhD; Paul G. Yock, MD

Activities: Clinical Research:

- Intravascular Ultrasound Core Laboratory

- Clinical Testing of Medical Devices

Experimental Research:

- Atherosclerotic Plaque Characterization

- Development of New Devices for Coronary Interventions

- Percutaneous Treatment of Mitral Regurgitation

Duration: October 1999 to April 2001.

EMPLOYMENT

Staff Physician Cardiovascular Diseases

Cardiac Catheterization & Angiography Laboratory

Hospital Angeles de Tijuana

Tijuana, BC, Mexico

December 2005 to Present

Medical Director, Field Advanced Stent Technologies, Inc.

6900 Koll Center Parkway. Suite 415

Pleasanton, CA 94566

(Acquired by Boston Scientific in December 2004)

July 2003 to December 2004.

Staff Physician Cardiac Catheterization Laboratories

Institute of Cardiovascular Sciences

Del Prado Hospital

Tijuana, BC, Mexico

July 2003 to Present

Consulting Physician Division of Cardiovascular Medicine

Cardiac Catheterization & Angiography Laboratory

Almater Hospital

Mexicali, BC, Mexico

July 2003 to Present

Medical Adviser Ensure Medical, Inc.

762 San Aleso Ave.

Sunnyvale, CA 94085

July 2003 to Present

Medical Adviser Edwards LifeSciences, Inc.

Division of Endovascular Technology

1 Edwards Way

Irvine, CA 92614

July 2003 to Present

Director, Research Institute of Cardiovascular Sciences

Del Prado Hospital

Tijuana, BC, Mexico

January 2004 to December 2005

PUBLICATIONS:

1. Luna J, Lisker M, Guevara L, Uribe M. Amibiasis intestinal [Intestinal amebiasis], en: Misael Uribe

(ed) Medicina Interna. Editorial Médica Panamericana. 1995.

2. Luna J, Uribe M. Leptospirosis, en: Misael Uribe (ed) Medicina Interna. Editorial Médica

Panamericana. 1995.

3. Luna J, Uribe M. Pseudotumor cerebri, en: Misael Uribe (ed) Medicina Interna. Editorial Médica

Panamericana. 1995.

4. Luna J, Zenteno E. Farmacopea de Urgencias [Emergency Room Pharmacopea], en: Instituto

Nacional de la Nutrición - Salvador Zubirán: Manual de Terapéutica y Procedimientos de Urgencias.

2ª Edición. Editorial Interamericana - Mc Graw-Hill. 1996.

5. Juárez Herrera U, Lasses y Ojeda LA, Rosas Peralta M, Luna-Guerra J, López Rodríguez MC,

Chuquiure Valenzuela E, Martínez Sánchez C, González Pacheco H, Jiménez MG, Reyes PA, Lupi

Herrera E. Utilidad de la determinación cualitativa rápida de troponina-T, fracción MB de creatina

fosfocinasa y mioglobina en los síndromes isquémicos coronarios agudos [Utility of a rapid bedside

assay of cardiac T-troponin, MB-creatinphosphokinase and myoglobin in acute ischemic coronary

syndromes]. Arch Inst Cardiol Méx 1998;68(6):473-481.

6. Martínez-Ríos MA, Eid-Lidt G, Luna-Guerra J, Villavicencio-Fernández R, Ban Hayashi E, Gaspar

Hernández J, Peña Duque MA. Beneficio del Stent Coronario en la Reducción de Complicaciones

Cardíacas Mayores en Síndromes Coronarios Agudos [Benefit of Coronary Stenting in the

Reduction of Major Adverse Cardiac Events in Acute Coronary Syndromes]. Arch Inst Cardiol Méx

1999;69(2):121-126.

7. Tovar Blanco S, Marenco RE, Peña Duque MA, Luna-Guerra J, Vázquez Sánchez J, Martínez Ríos

MA. Arteriografía Coronaria y Aortografía por Vía Translumbar en una Paciente con Arteritis de

Takayasu [Translumbar Coronary Arteriography in a Patient with Takayasu’s Arteritis]. Arch Inst

Cardiol Méx 1999;69(2):149-152.

8. Martínez-Ríos MA, Tovar S, Luna J, Eid-Lidt. Percutaneous Mitral Commissurotomy. Cardiol Rev.

1999;7(2):43-54.

9. Martinez Sanchez C, Martinez C, Lasses A, de la Pena E, Ramirez J, Luna J, Gonzalez H, Chuquiure

E, Juarez Herrera U, Martinez Rios MA, Gonzalez Romero S, Lupi E. [Comparative analysis of

reperfusion time in primary angioplasty vs thrombolysis. Success vs time]. Arch Inst Cardiol Mex

1999;69(5):438-444.

10. Martínez-Ríos MA, Luna J. Percutaneous Balloon Mitral Valvuloplasty: Long Term Follow-up.

Cardiol Rev 1999;7(4):457.

11. Luna-Guerra J, Henne O. Cirrosis Congestiva [Congestive Liver Cirrhosis], en: Misael Uribe (ed),

Texto de Gastroenterología. Editorial Médica Panamericana. 2000.

12. Eid-Lidt G, Villavicencio R, Ponce de León, S, Gaspar J, Luna-Guerra J, Ban Hayashi E, Peña-

Duque MA, Martínez-Ríos MA. Comparative trial of stent-like balloon angioplasty Vs coronary

stenting for acute myocardial infarction. Catheter Cardiovasc Interv. 2001;53(2):149-154.

13. Luna-Guerra J, Lopez Jimenez F. [Intravascular treatment with ionizing radiation for the

prevention of coronary restenosis: a new story with a known character]. Rev Invest Clin

2001;53(3):206-208.

14. Fearon WF, Luna J, Samady H, Powers ER, Feldman T, Dib N, Tuzcu EM, Cleman MW, Chou TM,

Cohen DJ, Ragosta M, Takagi A, Jeremias A, Fitzgerald PJ, Yeung AC, Kern MJ, Yock PG.

Fractional flow reserve compared with intravascular ultrasound guidance for optimizing stent

deployment. Circulation. 2001;104(16):1917-1922.

15. Courtney BK, Robertson AL, Maehara A, Luna J, Kitamura K, Morino Y, Achalu R, Kirti S, Yock

PG, Fitzgerald PJ. Effects of transducer position on backscattered intensity in coronary arteries.

Ultrasound Med Biol. 2002;28(1):81-91.

16. Dambrin C, Klupp J, Bîrsan T, Luna J, Suzuki T, Lam T, Stähr P, Hausen B, Christians U,

Fitzgerald P, Berry G, Morris R. Sirolimus (Rapamycin) Monotherapy Prevents Graft Vascular

Disease in Nonhuman Primate Recipients of Orthotopic Aortic Allografts. Circulation

2003;107(18):2369-2374.

17. Klupp J, Dambrin C, Hibi K, Luna J, Suzuki T, Hausen B, Bîrsan T, van Gelder T, Fitzgerald PJ,

Berry G, Morris RE. Treatment by Mycophenolate Mofetil of Advanced Graft Vascular Disease in

Non-Human Primate Recipients of Orthotopic Aortic Allografts. AmJ Transplant 2003; 3: 1–13.

18. Luna J, Yeung AC. Intracoronary Ultrasound, In-stent restenosis, in: Fernando Alfonso (ed),

Intracoronary Diagnostic Techniques. McGraw-Hill Publishing Co. 2003. ISBN 8448604865.

19. Luna-Guerra J, Guarner-Lans V. Abastecimiento de Oxígeno al Miocardio [Myocardial Oxygen

Delivery], in Ferez-Santander SM, Lupi-Herrera E (eds), El comportamiento del miocardio en la

isquemia y en la reperfusión [Myocardial Behavior During Ischemia and Reperfusion]. Elsevier.

Madrid, Spain. 2004. ISBN 84-8174-778-5

20. Luna-Guerra J, Ferez-Santander SM. Precondicionamiento Isquémico [Ischemic Preconditioning],

in Ferez-Santander SM, Lupi-Herrera E (eds), El comportamiento del miocardio en la isquemia y en la

reperfusión [Myocardial Behavior During Ischemia and Reperfusion]. Elsevier. Madrid, Spain. 2004.

ISBN 84-8174-778-5

21. Ferez-Santander SM, Luna-Guerra J, Peña-Duque MA. Cardioprotección-Precondicionamiento en

los Mecanismos de Adaptación del Miocardio a la Isquemia [Cardioprotection, Preconditioning in

Myocardial Adaptive Mechanisms to Ischemia], in Ferez-Santander SM, Lupi-Herrera E (eds), El

comportamiento del miocardio en la isquemia y en la reperfusión [Myocardial Behavior During

Ischemia and Reperfusion]. Elsevier. Madrid, Spain. 2004. ISBN 84-8174-778-5

22. Luna-Guerra J. Tipos de Flujo Miocárdico Posreperfusión (Escala TIMI de flujo) [Post-reperfusion

Myocardial Flow Grading (TIMI flow score)], in Ferez-Santander SM, Lupi-Herrera E (eds), El

comportamiento del miocardio en la isquemia y en la reperfusión [Myocardial Behavior During

Ischemia and Reperfusion]. Elsevier. Madrid, Spain. 2004. ISBN 84-8174-778-5

23. Luna-Guerra J. Fenómeno de No Reflujo [No-Reflow Phenomenon], in Ferez-Santander SM, Lupi-

Herrera E (eds), El comportamiento del miocardio en la isquemia y en la reperfusión [Myocardial

Behavior During Ischemia and Reperfusion]. Elsevier. Madrid, Spain. 2004. ISBN 84-8174-778-5

24. Ikeno F, Kim YH, Luna J, Condado JA, Colombo A, Grube E, Fitzgerald PJ, Park SJ, Yeung AC.

Acute and long-term outcomes of the novel side-access (SLK-View™) stent for bifurcation coronary

lesions: A multicenter nonrandomized feasibility study. Catheter Cardiovasc Interv

2006;67(2):198-206.

PRESENTATIONS AT INTERNATIONAL SCIENTIFIC MEETINGS:

"Coronary stenting in acute myocardial infarction versus ‘stent-like’ coronary balloon angioplasty",

presented at the 47th Annual Scientific Session (American College of Cardiology), held in Atlanta,

Georgia. March 29 - April 1, 1998.

"Influence of non-insulin-dependent diabetes mellitus on in-hospital mortality after primary angioplasty for

acute myocardial infarction", presented at the XIIIth World Congress of Cardiology (International Society

and Federation of Cardiology), held in Rio de Janeiro, Brazil. April 26 - 30, 1998.

"The analysis of the QT interval dispersion is a predictor of ventricular arrhythmias during primary

angioplasty", "Stenting versus "stent-like" coronary balloon angioplasty in acute myocardial infarction",

"Time interval between symptoms onset and reperfusion with primary angioplasty for acute myocardial

infarction: Differences between day and night shifts", "Usefulness of a rapid bedside assay of troponin-T,

creatinphosphokinase-MB and myoglobin in acute ischemic syndromes", presented at the XIIIth World

Congress of Cardiology (International Society and Federation of Cardiology), held in Rio de Janeiro,

Brazil. April 26 - 30, 1998.

"Clinical Experience with a Novel Stent and Delivery System for Bifurcation Lesions", presented at TCT

2001 (Transcatheter Therapeutics), held in Washington, DC. September 11-16, 2001.

"Intravascular Ultrasound Assessment Five Years After Intracoronary Gamma Radiation Therapy",

presented at the 51th Annual Scientific Session (American College of Cardiology), held in Atlanta, GA.

March 25-29, 2002.

"A Percutaneous Approach for the Treatment of Mitral Regurgitation Evaluated in the Healthy Ovine

Model", presented at Transcatheter Therapeutics, held in Washington, DC. September 24-28, 2002.

PROFESSIONAL AFFILIATIONS AND CERTIFICATIONS

1. American College of Physicians

2. Asociación de Medicina Interna de México

[Internal Medicine Association of Mexico]

3. Consejo Mexicano de Medicina Interna

[Mexican Board of Internal Medicine]

4. Educational Commission for Foreign Medical Graduates

United States Medical Licensing Examination

5. Consejo Mexicano de Cardiología

[Mexican Board of Cardiology]

6. Sociedad Mexicana de Cardiología

[Mexican Society of Cardiology]

7. American College of Cardiology

8. Society for Cardiovascular Angiography and Interventions

9. Sociedad Latinoamericana de Cardiología Intervencionista

[Latin-American Society of Interventional Cardiology]

10. Sociedad de Cardiología Intervencionista de México

[Mexican Society of Interventional Cardiology]